Synthesis of the Insecticide Prothrin from 5-(Chloromethyl)furfural (CMF)
J Agric Food Chem. 2014 Jan 3.: Prothrin, a synthetic pyrethroid insecticide, was synthesized from the biomass-derived platform chemical 5-(chloromethyl)furfural in six steps and overall 65% yield. Two structural analogues of prothrin were also prepared following the same synthetic approach. Preliminary testing of these furan-based pyrethroids against the yellow fever mosquito Aedes Aegypti indicates promising insecticidal activities.
References: J Agric Food Chem. 2014 Jan 3  Example: Highly efficient dehydration of carbohydrates to 5-(chloromethyl)furfural (CMF), 5-(hydroxymethyl)furfural (HMF) and levulinic acid by biphasic continuous flow processing, Green Chemistry, Issue 5, 2011 (For our clients: Download publication and supporting information here).
Biomass to Pharmaceuticals
From Biomass to Medicines
Since 2001, DalinYebo provides knowhow:
To convert biomass to value added chemical products and applications that are used in industries such as steel, wood, pharmaceutical, automotive, agricultural chemicals, industrial chemicals, etc.
For the agri (biomass) processing, sugar, pulp&paper, etc. industries, we provide knowhow and technology to convert (residual) biomass to chemicals and energy.
For owners of biomass we offer technology and market access, creating investment opportunities in the cleantech space.
The essential technical challenge facing us, and the world in general, is the complete beneficiation of cellulosic material. We strive to provide viable and practical solution. Contact us to discuss the economic potential of your biomass.