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Biomass to Market

Multistep Synthesis

Furfual: 6 Steps to Medicine Furfual: 6 Steps to Medicine (Image by DalinYebo)
Turing Biomass into Medicine

A method of synthesis has been developed to turn furfual into indolo[3,2-c]quinolines (an antimalarial alkaloid isocryptolepine and its derivatives), reports the Journal of Organic & Biomolecular Chemistry (Issue 36, 2012).

The work was undertaken by a team of Russian scientists who are "dealing with the development of procedures for transformations of furfural into diverse furan derivatives and a broad variety of other heterocycles.4 Recently, we have discovered a simple route from furfural (1) to 3-(2-acylvinyl)-2-(hetero)arylindoles" (Org. Biomol. Chem., 2012, 10, 7262)